This individual's Ydna is : --> F --> IJ --> J --> J2 --> J2b
Gender Score is 1.000
R116_Italy.txtis 100.000% Likely to be Male
R116_Italy.txtis 0.000% Likely to be Female
0 A variants out of 0 Total
0 B variants out of 2 Total
0 C variants out of 17 Total
0 D variants out of 0 Total
0 E variants out of 67 Total
0 E1b variants out of 2 Total
0 E3b variants out of 2 Total
69 F variants out of 69 Total
2 G variants out of 105 Total
0 H variants out of 4 Total
18 IJ variants out of 18 Total
0 I variants out of 104 Total
0 I1 variants out of 41 Total
0 I2 variants out of 7 Total
57 J variants out of 57 Total
0 J1 variants out of 5 Total
0 J1a variants out of 0 Total
0 J1b variants out of 0 Total
4 J2 variants out of 4 Total
0 J2a variants out of 5 Total
9 J2b variants out of 9 Total
0 K variants out of 2Total
0 L variants out of 6Total
0 N variants out of 9Total
0 O variants out of 41Total
0 Q variants out of 11Total
0 Q1 variants out of 5Total
0 Q2 variants out of 1Total
0 R variants out of 38Total
0 R1a variants out of 0Total
0 R1b variants out of 9Total
0 R2 variants out of 8Total
Results Mental Health
AA in COMT's rs165599 variation, which leads to a decreased risk of Schizophrenia and Bipolar disorder.
AA or 2 derived No Go learner variants in DRD2's Pro319Pro variation, which causes a significant reduction in the number of D2 dopamine receptor sites in the brain, a reduction in the risk of schizophrenia, and an increased likelihood of No Go learning, which is the ability to withhold a response when it's not warranted.
AG in DRD2's rs6275 variation, meaning intermediate number of dopamine D2 receptors and average risk of Schizophrenia.
CC in DRD2's rs2514218, higher odds of Schizophrenia
GG in rs4648317 of DRD2, which is the typical for most humans, and leads to a slightly lower risk of Schizophrenia and nicotine dependence.
CC in rs1076560 of DRD2, which is the typical for most humans leading to a slightly higher number of D2 dopamine receptors and better memory performance.
CC in rs5326 of DRD1, which is the typical for most humans and leads to a slightly lower risk of various mental health conditions.
AA in rs686 of Dopamine Receptor D1 gene, which leads to a higher likelyhood of Autism.
TT in rs4532 of DRD1, a typical associated with slightly higher odds of Autism and tobacco addiction.
GG in rs265981 of DRD1, which is the typical for most humans, and leads to a slightly higher risk of Schizophrenia and nicotine dependence.
TT in rs6280 of DRD3, a typical associated with a slightly lower risk of OCD and intellectual disability.
AA in DRD3's rs167771 variation, mostly a Eurasian , increases the risks of autism and autistic personality traits such as rigid behavior.
CC in DRD5's rs6283. Higher odds of ADHD; mechanism of action is not exactly known
TC, or heterozygous in rs2129785, a rare that leads to long form 5-HTTLPR and a significantly lower risk of depression.
CC in rs6311 of HTR2A, robustly increased risk of suicidal behavior and depression. 3.6x increased risk of sexual dysfunction when taking SSRI Antidepressants
CC in rs9834970 of TRANK1, slightly higher odds of Bipolar disorder and Schizophrenia
GG in rs75459873, no risk variants for psychosis in MIR378F. Very typical genotype.
Results Mental Health - Autism Only
CT in rs4307059, 1.19x risk of Autism
TT in rs10513025, typical , normal (higher) risk of autism.
AA in rs7794745, slightly decreased risk of autism.
CC in rs1804197, common genotype. Normal (lower) risk of autism.
AA in rs2217262, typical genotype. Average (higher) risk of autism.
TT in rs921451, More likely to smoke heavily if is a smoker.
CC in rs1451371, lower tendency to smoke heavily if is a smoker.
AA in rs2060762, lower tendency to smoke heavily if is a smoker.
Results For Lactose Persistence
GG in MCM6's rs4988235 variation, which means this individual does not carry the European lactose persistence mutation.
CC in MCM6's rs182549, This Individual does not have any derived variants for European lactose persistence.
Results for OXTR - The Empathy Gene
GG in rs1042778 of OXTR, higher oxytocin and empathy
TT in OXTR's rs13316193, a associated with decreased OXTR expression and lower levels of empathy, as well as higher risk of autism spectrum disorder.
GG in OXTR's rs7632287 variation, which means this individual has 2 variants for lower levels of empathy at this variation.
Results for Diabetes
GG in rs12255372, decreased risk of Type 2 Diabetes.
GG in rs35011184, lower odds of Type 2 diabetes and obesity.
AA in rs17388568, 1.6x risk of type-1 diabetes.
GG in rs7754840, which means this individual has two variants for lower odds of type 2 diabetes.
CC in rs7903146, a associated with lower risk of type 2 diabetes.
Results for Hemochromatosis
CC in HFE's His63Asp, which means this individual does not have any H63D variants and most likely doesn't have hemochromatosis.
Results for Alzheimers
CC in rs7412, which means no APOE2 alleles in Arg176Cys variation of the APOE gene and lower, or in other terms, normal odds of alzheimers disease.
TT in rs3025786, which is a typical for most humans and leads to average (slightly increased) risk of Alzheimers.
GG in PLD3's rs145999145 variation, which means this individual has a lower risk of Alzheimers.
AA in TOMM40's rs2075650, slightly decreased odds of Alzheimer's disease.
CC in rs75932628, normal (Slightly lower) risk of Alzheimer's disease
CC in rs63750847, no variants for reduced risk of Alzheimer's disease. Normal (Higher) odds of Alzheimers
Multiple sclerosis
Cardio-Vascular Disease Panel
AA in rs662799, normal (Lower odds of heart attack and obesity)
GG in rs602633, 0 risk variants for Coronary Heart Disease (Odds ratio = 1.11 for every T allele). common genotype.
GG in rs10958409, normal (lower) risk of brain aneurysm, risk allele is A
AA in rs9298506, normal (higher) risk of aneurysm.
TT in rs6475606, increased risk for Coronary artery disease.
CC in rs9315204, lower risk of aneurysm, common genotype.
GG in rs10757274, 1.3x increased risk for heart disease.
GG in rs2383206, 1.7x increased risk for heart disease.
GG in rs10757278, 1.6x risk for Heart Attack; 1.3x risk for Abdominal Aortic Aneurysm and Brain Aneurysm.
TC in rs1800787, carrier of risk variant for carotid arthery disease (T), most likely doesn't have carotid arthery disease.
AA in rs5082, Higher (normal) risk of heart disease.
Myopia Panel (Ordered from highest to lowest impact)
CC in rs7744813, which leads to an increase in the risk of myopia.
AT, or heterozygous in rs524952, which means a slightly decreased risk of myopia.
AA in rs4803455, two alleles that protect from Myopia.
Miscellaneous
(Don't voice this in video!!) CC in rs9332964, no micropenis.
TT in rs10784502, smaller cranium and lower IQ.
GG in rs324640, 8 points higher IQ than individuals with 'AA' .
TT in rs1815739, Impaired muscle performance. Likely endurance athlete.
TT in rs10427255, likely does not have photic sneeze reflex.
AA in SCN9A rs6746030 variation, 2 variants for increased pain sensitivity.
TT, no MYBPC2 mental retardation variants, likely healthy.
AA genotype in EDAR's rs3827760, Likely no shovel shaped incissors and not East Asian in ancestry
AC genotype in EDAR's rs260690, Likely not European facial traits. Rare for Europeans, common for East Asians.
GG in rs671 variation, Not an Asian flusher, lower odds of Alcoholism. Normal risk of Esophageal Cancer.
AA in rs1080066, average brain volume (slightly smaller). common genotype.
Drug Responce
When treated with metoprolol
rs1801252(A;A) and rs1801253(C;C) carriers: 15 point drop in Blood Pressure rs1801252(A;G) and rs1801253(C;C) carriers: 9 point drop in Blood Pressure rs1801252(A;A) and rs1801253(C;G) carriers: 6 point drop in Blood Pressure rs1801252(A;G) and rs1801253(C;G) carriers: 1 point drop in Blood Pressure
Your genotypes are : AA in rs1801252 & CC in rs1801253
TT in rs9919007, not blood type O. 0.74 accuracy
CC in rs10156191 of AOC1, normal (increased) DOA activity, normal genotype. Tolerates NSAIDs.
TT in rs5092, more likely to gain weight if taking olanzapine.
CC in rs4765623, significantly more likely to gain weight if taking olanzapine.
GG in rs518147, significantly higher odds of weight gain if taking olanzapine.
AA in rs2241802, lower odds of methamphatamine induced psychosis.
GG in rs135745, lower susceptibility to methamphetamine induced psychosis.
Albinism & Atypical Traits Panel
CC in OCA2's rs121918166, Not Carrier of an oculocutaneous Albinism Type II mutation.
AA in TYR's rs28940881 variation, which means this individual does not have any Tyrosinase-negative oculocutaneous albinism mutations.
AA in TYR's rs28940878 variation, which means this individual does not have any Tyrosinase-negative oculocutaneous albinism mutations.
CC in TYR's rs104894313, Not Carrier of an oculocutaneous Albinism Type 1B mutation.
CC in TYRP1's rs104894130, which means this individual lacks variants for Oculocutaneous albinism type 3, and is not albino.
AA in rs987525, which leads to 6x increased risk for cleft lip.
CC in TYRP1's rs387907171, not a Carrier of melanesian blond hair variants.
Familiar Mediterranean Fever Panel
0 risk variants in rs104895094.
0 risk variants in rs61752717
0 risk variants in rs28940579.
0 risk variants in rs28940578.
0 risk variants in rs61732874.
0 risk variants in rs104895083.
0 risk variants in rs104895097.
0 risk variants in rs104895085
0 risk variants in rs104895081
0 risk variants in rs11466024
0 risk variants in rs79681911
0 risk variants in rs4149584
MTHFR panel
AG in MTHFR's rs1801133, 65% efficiency in processing folic acid. Slightly higher than average odds for a variety of illnesses from autism to coronary heart disease.
GG in MTHFR's rs1801131, Number of risks associated with impaired folate metabolism. Cancer, cleft lip, dementia, arthritis, heart disease risks.
AA in rs17367504, common , average (higher) blood pressure.
Cancers Panel
0 risk variants in Q356R of BRCA1
0 risk variants in BRCA1's D693N.
1 risk variant in K1183R of BRCA1
1 risk variant in S1613G of BRCA1
0 risk variants in N372H of BRCA2
CC in rs1042522 of TP53. Uncommon genotype. Live 3 years longer. Chemotherapy is more effective.
0 risk variants in S707P
AA in rs995030, 6 times Reduced risk of testicular cancer
CC in rs3782179; 9x lower odds of testicular cancer risk for men
GG in rs4474514, reduced testicular cancer risk for men
Leukemia Panel
no NQO1*3 alleles, average odds of leukemia.
TT in rs4132601, common -> lower risk of leukemia.
TT in rs7089424, common/normal and lower risk of Leukemia.
AA in rs2239633, lower odds of leukemia (~0.7x).
Rare diseases/traits Panel
GG in rs10033464, 0.92x decreased risk of Atrial Fibrillation and cardioembolic stroke.
GG in rs13078881, Healthy - no Biotinidase deficiency.
CC in rs10156191 of AOC1, normal (increased) DOA activity, normal genotype. Tolerates NSAIDs.
CC in rs104894635, no risk variants for Sanfilippo syndrome
No von Gierke's disease. CC in Arg83Cys of glucose-6-phosphatase G6PC gene.
GG in Cys1036Phe of BLM, not a carrier of variants for Bloom syndrome.
CC in rs1800546, normal.
TT in rs74315405, no Gerstmann–Straussler–Scheinker syndrome.
GG in rs3764147, 2 risk variants for Leprosy.
GG in rs11606250, most common , but higher risk for certain autoimmune diseases.
AA, 0 risk variants in rs2302009.
Celiac Disease Panel
AA in rs13119723, lower (normal) risk for celiac disease. 0 risk variants
No risk variants in R262W
Allergies Panel
TG in rs2155219, 1 allele for higher odds of allergies. Odds Ratio for every T allele = 1.18
CC in rs17513503, lower odds of allergies; common
Androgen Receptor Gene (AR) Panel
AA in rs6152, won't go bald.
CC in rs137852591, very typical ; no Androgen insensitivity.
GG in rs9332969, normal , no Reifenstein syndrome.
GG in rs9332971, normal , no Reifenstein syndrome.
Crohn's Disease Panel
CC in NOD2's Arg702Trp. Typical (lower) risk for Crohn's disease.
Canavan Syndrome Panel
AA in rs63751297, 0 risk variants.
0 risk variants in Y231X.
0 risk variants in A305E.
0 risk variants in E285A.
If you have more than 0 risk variants for Canavan syndrome, that is cause for concern. May be the result of genotyping errors depending on the chip you tested with.
HIV & AIDS Panel
HIV does not develop and transition into AIDs the same way with every organism. Some are predisposed to larger viral load and quicker compromisation of the immune system while others are more resistant.
0 protective variants in C927T (Bad), most typical genotype.
GG in rs2572886, Good , 0 risk variants (A), common.
Muscular Dystrophy Myopathies
0 risk variants in rs121913574
0 risk variants for Duchenne muscular dystrophy in rs1800278
0 risk variants in rs28937903
0 risk variants in rs28937904
0 risk variants in rs28928901
0 risk alleles in rs2296949
0 risk alleles in rs104894466
0 risk variants in rs193922094
Found : 2 risk variants for adrenoleukodystrophy out of 22 Total
If you have risk variants here, it is most likely caused by miscalls in your raw data.
Since ADL is an X-linked condition, males can not be carriers. If you are male over the age of 20 and see risk variants here, it is due to miscalls. Otherwise you would be dead.
Colorblindness Panel
0 risk variants in OPN1LW out of 0
0 risk variants in OPN1MW out of 0
0 risk variants in OPN1SW out of 2
FTO Gene Panel
GG in rs1121980, lower BMI, decrease in the risk of obesity
Within PFKP Gene - also implicated in Obesity
GG in rs6602024, lower BMI
Others also implicated in Obesity
AA in rs4994, typical genotype - lower odds of obesity.
TT in rs1799883, Two copies of the Thr allele in the FABP2 is associated with significantly increased sensitivity to saturated fats. Also contributes to increased refined carb sensitivity.
TT in rs6232, lower risk of obesity and insulin sensitivity
Syncope Panel
A syncope, commonly known as fainting, is a temporary loss of consciousness and muscle tone caused by a brief reduction in blood flow to the brain. This sudden and temporary loss of consciousness typically results from a drop in blood pressure, leading to a momentary interruption of oxygen and nutrient supply to the brain. Syncope episodes are often brief, lasting only a few seconds to a couple of minutes, and individuals usually recover spontaneously once blood flow is restored. Various factors, such as dehydration, low blood sugar, or sudden changes in body position, can contribute to the occurrence of syncope.
Used 3 snps in the following prediction
Syncope risk is 1.114 times the average
Bio Traits Panel
GG in rs66800491, lower (typical) odds of motion sickness (This is the variation with highest impact for motion sickness)
CC in rs307377, common in complete genomics - no extraordinary tasting ability
AA in rs1061147, 2.76x increased risk for Age Related Macular Degeneration.
AA in rs662799, normal (Lower odds of heart attack and obesity)
TT in rs2282679 of GC gene, normal levels of Vitamin D.
GG in rs12785878, higher levels of Vitamin D.
AA in rs10741657, tend to have higher vitamin D levels
TT in rs7129781, decreased odds of Vitamin D insufficiency
